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关于小儿原发性血小板减少性紫癜(以下称ITP)的治疗还有很多不同意见。本文以我院治疗的ITP病例为主,研究了其临床过程、治疗方法,特别对初期使用类固醇(以下称S剂),切脾的适应症,血浆疗法的疗效,加以研究。1977年4月~1980年11月,作者治疗过根据厚生省ITP调查研究班的诊断标准,诊断为ITP的27例。发病6个月,血小板减少,有出血倾向者为慢性型。27例中急性型15例(56%)、慢性型(包括复发病例)10例(37%),目前仍在观察中2例。年龄:3个月~9岁,3~5岁占40%以上。急性型15例中有13例在病初即使用S剂,用药6周后全部病例血小板数均达10万以上(1周以内者20%,2周以内60%);未使用者2例,血小板数未见增加,使用S剂后分别
On the treatment of pediatric primary thrombocytopenic purpura (hereinafter referred to as ITP) there are many different opinions. In this paper, ITP cases treated mainly in our hospital, studied its clinical course, treatment, especially for the initial use of steroids (hereinafter referred to as S agent), spleen indications, the efficacy of plasma therapy, to be studied. From April 1977 to November 1980, the authors treated 27 patients diagnosed with ITP based on the diagnostic criteria of the ITP Surveys at the Ministry of Health and Welfare. The onset of 6 months, thrombocytopenia, bleeding tendency for chronic type. Of the 27 cases, 15 (56%) were acute and 10 (37%) were chronic, including relapsed, and 2 are still under observation. Age: 3 months to 9 years old, 3 to 5 years old accounted for more than 40%. Thirteen of the 15 acute cases were treated with S agents at the beginning of the illness. The number of platelets in all the cases reached more than 100,000 (6% within 1 week, 60% within 2 weeks) after 6 weeks of treatment. No increase in platelet count, respectively, after using the S agent