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目的探讨支气管哮喘合并阻塞性睡眠呼吸暂停综合征(OSAHS)的临床特点及其影响因素。方法选取2010年4月—2015年4月宝丰县人民医院重症医学科收治的支气管哮喘患者80例,对其临床资料进行回顾性分析,观察组为45例合并OSAHS者,对照组为35例未合并OSAHS者,比较两组临床资料及肺功能指标,分析支气管哮喘合并OSAHS的临床特点及影响因素。结果 45例哮喘合并OSAHS临床特点:夜间发作占31.1%,日间发作占22.2%;体质指数(BMI)在25kg/m2及以上占80.0%。单因素、多因素Logistic多因素回归分析显示,过敏性鼻炎及肥胖是支气管哮喘并发OSAHS的独立危险因素(P<0.05)。结论支气管哮喘合并OSAHS发生率较高,其独立影响因素为过敏性鼻炎与BMI病史。
Objective To investigate the clinical characteristics and influential factors of bronchial asthma combined with obstructive sleep apnea syndrome (OSAHS). Methods From April 2010 to April 2015, 80 patients with bronchial asthma admitted to the Department of Critical Care Medicine of Baofeng County People’s Hospital were retrospectively analyzed. The data of 45 patients with OSAHS in the observation group and 35 patients in the control group Patients with OSAHS were compared between the two groups of clinical data and lung function, analysis of bronchial asthma combined with OSAHS clinical features and influencing factors. Results The clinical features of 45 asthma patients with OSAHS were: nocturnal episodes accounted for 31.1%, day seizures accounted for 22.2%, and body mass index (BMI) accounted for 80.0% for 25kg / m2 and above. Univariate and multivariate logistic regression analysis showed that allergic rhinitis and obesity were independent risk factors for OSAHS complicated with bronchial asthma (P <0.05). Conclusion The incidence of bronchial asthma combined with OSAHS is high, and the independent influencing factors are history of allergic rhinitis and BMI.