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目的观察常规药物流产后加服米索前列醇对流产结局的影响。方法将300例早孕妇女分为观察组(150例)和对照组(150例)。常规药物流产用药后,口服米索前列醇600μg。观察组于口服米索前列醇6小时后加服米索前列醇600μg,对照组不再加服。结果完全流产率观察组为97.33%,对照组为88.67%,两组间有显著性差异(P<0.05),平均阴道出血时间,观察组(8.8±4.1)d,对照组(15.8±5.2)d,两组间有显著差异(P<0.05),阴道出血量两组间有显著差异(P<0.05),不良反应两组无显著差异(P>0.05)。结论加服米索前列醇可提高完全流产率,缩短药物流产后阴道出血时间和减少出血量,加药后不增加不良反应,是值得推广的药物流产方法。
Objective To observe the effect of misoprostol on abortion outcome after conventional medical abortion. Methods 300 pregnant women were divided into observation group (150 cases) and control group (150 cases). Conventional medical abortion medication, oral misoprostol 600μg. The observation group was given 600 μg of misoprostol 6 hours after oral misoprostol, and the control group no longer served. Results The rate of complete abortion was 97.33% in the observation group and 88.67% in the control group, with significant difference between the two groups (P <0.05), mean vaginal bleeding time (8.8 ± 4.1) d and control group (15.8 ± 5.2) d, There was significant difference between the two groups (P <0.05). There was significant difference between the two groups of vaginal bleeding (P <0.05). There was no significant difference between the two groups (P> 0.05). Conclusion Adding misoprostol can increase the rate of complete abortion, shorten the vaginal bleeding time after medical abortion and reduce the amount of bleeding, add no adverse reactions after drug addition, is worth promoting the method of medical abortion.