治疗相关性骨髓增生异常综合征和急性非淋巴细胞性白血病的细胞遗传学研究

• 作 者: 刘泽林
• 出 处: 国外医学.输血及血液学分册
• 发表日期: 1991年01期
• 关键词: 细胞遗传学研究 ANLL 免疫表型 正常核型 何杰金病 原发肿瘤 细胞化学 染色体异常 核型异常 多发性骨髓瘤

对27例治疗可疑相关性骨髓增生异常综合征(t-MDS)或急非淋(t-ANLL)者进行细胞遗传学研究,其中12例经形态学、细胞化学和免疫表型分析确诊为t-MDS或t-ANLL,其它15例具有正常核型,结合形态岁和免疫表型特点符合暂时性细胞减少症。确诊为t-MDS或t-ANLL的12例患者中8例原发肿瘤为何杰金病(HD),其余4例分别为多发性骨

Twenty-seven patients were studied by cytogenetics for t-MDS or t-ANLL, of which 12 were diagnosed by morphological, cytochemical and immunophenotypic analysis as t -MDS or t-ANLL, the other 15 patients with normal karyotype, combined with age and immunophenotype consistent with transient cytocytosis. Eight of the 12 patients diagnosed with t-MDS or t-ANLL had Hodgkin’s disease (HD) and the remaining 4 were multiple bone