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妊娠期肝脏病对产妇、胎儿与围产期胎儿预后均有一定影响。Sherlock将其分为妊娠期特发性黄疸、妊娠期黄疸、肝脏病合并妊娠。Steven建议在Sherlock分类的基础上分为妊娠特发性肝病、妊娠间发性肝病及肝胆疾病合并妊娠更符合实际的需要。一、正常妊娠时肝脏的变化约有三分之二的正常妊娠可出现“朱砂掌”及“蜘蛛痣”,并可随妊娠进行而加重,分娩后4～6周消失,这与妊娠期血循环中雌激素增加有关,妊娠可加重各器官的负担,但肝功能并无显著损害。未孕妇女肝血流量占心排出量的35％,而妊娠时仅占28％,多余的容量通过胎盘而分流。
Gestational liver disease on the mothers, fetuses and perinatal fetal prognosis have a certain impact. Sherlock divides it into gestational idiopathic jaundice, jaundice during pregnancy, and liver disease with pregnancy. Steven suggested based on Sherlock classification is divided into pregnancy-induced idiopathic liver disease, pregnancy-induced liver disease and hepatobiliary disease combined with pregnancy more realistic needs. First, changes in the liver during normal pregnancy About two-thirds of normal pregnancy may appear “cinnabar palm” and “spider mole” and may be aggravated with pregnancy, 4 to 6 weeks after childbirth disappeared, which is related to pregnancy blood circulation In the increase of estrogen, pregnancy can increase the burden on various organs, but no significant damage to liver function. Hepatic blood flow in nonpregnant women accounts for 35% of cardiac output, compared to 28% in pregnancy, with excess capacity being shunted through the placenta.