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目的探讨中枢神经细胞瘤临床诊断及治疗方法,以提高对本病的认识和诊疗水平。方法回顾总结我科9例患者,对临床表现、影像学表现、病理特征、治疗选择及预后分析,并综述文献报道。结果9例患者Syn抗体全部阳性,6例肿瘤全切患者2例行放疗,4例未行放疗,3例部分切除患者,1例行放疗后肿瘤完全消失,1例行伽玛刀治疗后3个月残瘤完全消失,生存病例随访12～56个月,未见肿瘤复发。结论中枢神经细胞瘤是一种倾向于良性的肿瘤,确诊需靠病理诊断,Syn抗体阳性,可作为确诊的重要标志;术中尽量全切肿瘤,解除梗阻性脑积水。肿瘤对放射治疗敏感,部分切除后进行放射治疗可收到较好效果,立体定向外科及伽玛刀治疗对一些残留肿瘤是一选择。
Objective To investigate the clinical diagnosis and treatment of central neurocytoma in order to improve the understanding of the disease and diagnosis and treatment. Methods Nine patients in our department were reviewed and reviewed. The clinical manifestations, imaging findings, pathological features, treatment options and prognosis were reviewed and reviewed. Results All the 9 patients were positive for Syn antibody, 6 patients underwent complete radiotherapy, 2 patients underwent radiotherapy, 4 patients underwent radiotherapy, 3 patients underwent partial radiotherapy and 1 patient underwent complete radiotherapy. One patient underwent gamma knife treatment Month of the complete disappearance of residual tumor survival cases were followed up 12 to 56 months, no tumor recurrence. CONCLUSIONS: Central neurocytoma is a benign tumor. Diagnosed by pathology, Syn antibody is positive and can be used as an important marker for diagnosis. Tumor resection is complete and the obstructive hydrocephalus is relieved during operation. Tumors are sensitive to radiation therapy, radiation therapy after partial resection can receive better results, and stereotactic surgery and gamma knife treatment is an option for some residual tumors.