论文部分内容阅读
目的探讨地塞米松联合人血丙种球蛋白治疗小儿特发性血小板减少性紫癜的疗效。方法将72例特发性血小板减少性紫癜患儿随机分为两组各36例,对照组给予地塞米松治疗,治疗组在地塞米松治疗的基础上加用人血丙种球蛋白治疗。比较两组出血控制时间、血小板计数变化、维持正常计数时间、有效率和不良反应等情况。结果治疗组出血控制时间、用药后血小板上升速度及血小板升至正常后持续时间、总有效率均明显优于对照组(P<0.05),且不良反应发生率低。结论地塞米松联合丙种球蛋白治疗小儿特发性血小板减少性紫癜疗效显著,能够快速提高血小板水平,缩短住院天数,提高治愈率。
Objective To investigate the efficacy of dexamethasone combined with human gamma globulin in the treatment of idiopathic thrombocytopenic purpura in children. Methods Seventy-two children with idiopathic thrombocytopenic purpura were randomly divided into two groups of 36 cases. The control group was treated with dexamethasone. The treatment group was treated with dexamethasone plus human gamma-globulin. The bleeding control time, platelet count change, normal counting time, efficiency and adverse reactions were compared between the two groups. Results The bleeding time, the rising rate of platelets after treatment and the duration of platelets rising to normal in the treatment group were significantly better than those in the control group (P <0.05), and the incidence of adverse reactions was low. Conclusion Dexamethasone combined with gamma globulin treatment of idiopathic thrombocytopenic purpura in children with significant effect, can rapidly increase platelet levels, shorten the length of stay, and improve the cure rate.