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目的探讨多潘立酮联合复方消化酶治疗功能性消化不良的临床效果。方法选择2009年11月～2010年7月收治的功能性消化不良患者110例,遵照知情同意原则分为两组,对照组52例采用多潘立酮治疗,观察组58例采用多潘立酮联合复方消化酶治疗,比较两组患者的临床治疗情况。结果观察组的治疗总有效率为98.3%,明显高于对照组的84.6%,两组比较有显著性差异(P<0.05);观察组的不良反应发生率为3.4%;对照组为5.8%,两组比较无显著性差异(P>0.05)。结论多潘立酮联合复方消化酶治疗功能性消化不良临床效果更佳,且无严重不良反应,值得临床关注。
Objective To investigate the clinical effects of domperidone combined with compound digestive enzymes in the treatment of functional dyspepsia. Methods One hundred and ten patients with functional dyspepsia who were admitted from November 2009 to July 2010 were divided into two groups according to the principle of informed consent. Fifty-two patients in the control group were treated with domperidone, 58 in the observation group were treated with domperidone and compound digestive enzyme, Compare the clinical treatment of two groups of patients. Results The total effective rate in the observation group was 98.3%, significantly higher than that in the control group (84.6%), with significant difference between the two groups (P <0.05). The adverse reaction rate in the observation group was 3.4% and in the control group was 5.8% , No significant difference between the two groups (P> 0.05). Conclusion Domperidone combined with compound digestive enzymes in the treatment of functional dyspepsia clinical effect is better, and no serious adverse reactions, it deserves clinical attention.