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应用自动血浆分离器对７４例类风湿关节炎（ＲＡ）和强直性脊柱炎（ＡＳ）共进行２７４人次血浆置换（ＰＥ），取得了显著疗效，显效率６３．５１％，有效率３３．７８％，无效２．７１％，总有效率９７．２９％。在ＰＥ时观察到在ＰＥ前病情活动期血清ｓＩＬ—２Ｒ浓度升高，并与血沉呈正相关（ｒ＝０．５４０，Ｐ＜０．１０）。研究指示：ｓｌＬ—２Ｒ浓度升高，可作为ＲＡ，ＡＳ患者病情活动及恶化的观察指标．
A total of 744 cases of rheumatoid arthritis (RA) and ankylosing spondylitis (AS) were subjected to plasma exchange (PE) with an automatic plasma separator. The effective rate was 63.51% and the effective rate was 33.78 %, Invalid 2.71%, the total efficiency of 97.29%. At PE, elevated serum sIL-2R levels were observed during the active phase of PE and were positively correlated with ESR (r = 0.540, P <0.10). Research indicates that: the concentration of slL-2R increased, as RA, AS patients with disease activity and deterioration of the indicators.