局部使用米替福新治疗腿部鳞状细胞癌的皮肤转移灶

• 作 者: Mahieu- Renard L. Richard M.- A. Dales J.- P. 王琼
• 机 构: Service de Dermatologie H.opital Sainte- Marguerite 270 boulevard de Sainte- Marguerite 13009 Marse
• 出 处: 世界核心医学期刊文摘(皮肤病学分册)
• 发表日期: 2005年08期
• 关键词: 米替福新 皮肤 鳞状细胞癌 胆碱磷酸 患者耐受性 乳腺癌 十六烷 化疗药物 个月 病例

Introduction. Miltefosine (Hexadecylphosphocholine) is a chemotherapy, which when applied locally, has demonstrated efficacy in the treatment of cutaneous metastases of breast cancer. Case report. A 79 year- old woman developed recurrent in transit cutaneous metastases of a squamous cell carcinoma on her left leg. All lesions completely resolved after topical applications of miltefosine. Tolerance was excellent and the patient remained disease- free 24 months after the end of the treatment. Discussion. Miltefosine, which might prove to be a simpleandeffectivealternativefortheusuallyheavytreatments proposed, warrants further assessment in this context.

Introduction to Miltefosine (Hexadecylphosphocholine) is a chemotherapy, which when applied locally, has demonstrated efficacy in the treatment of cutaneous metastases of breast cancer. Case report. A 79 year- old woman developed recurrent in transit cutaneous metastases of a squamous cell carcinoma on her left leg. All lesions completely resolved after topical applications of miltefosine. Tolerance was excellent and the patient remained disease-free 24 months after the end of the treatment. Discussion. Miltefosine, which might prove to be a simple an effective alternative to heartuallyheavytreatments proposed, warrants further assessment in this context.