Synthesis and Crystal Structure of 1,2,4,6-Tetraphenyl-2-hydroxy-8-azabicycle[3,2,1]octane

• 出 处: 结构化学
• 发表日期: 2001年04期
• 关键词: octane alkaloid membered skeleton slightly chair alkyl bonds valent distorted

The title compound (C31H29NO, Mr = 431.6) was synthesized and its crystal structure was determined by X-ray diffraction method. It crystallized in orthorhombic space group Pcab, with cell parameters: a = 10.579 (3), b = 18.514(7) , c = 23.93(1) ?, V = 4686.22(3) ?3, Z = 8, Dc = 1.223g/cm3, F(000) = 1840, μ = 0.68mm-1. The structure was solved by direct methods and refined by full-matrix least-squares method, and final R = 0.057, Rw = 0.060 for 2282 observed reflections with I ≥3.00σ(I). The molecular backbone is aza-bicycle [3,2,1]octane containing a chair-like six-membered aza-cycle conformation.

The crystallized in orthorhombic space group Pcab with cell parameters: a = 10.579 (3), b = 18.514 (7) The title compound (C31H29NO, Mr = 431.6) was synthesized and its crystal structure was determined by X-ray diffraction method. , C = 23.93 (1) ?, V = 4686.22 (3)? 3, Z = 8, Dc = 1.223 g / cm3, F (000) = 1840 and μ = 0.68 mm- 1. The structure was solved by direct methods and refined by full-matrix least-squares method, and final R = 0.057, Rw = 0.060 for 2282 observed reflections with I ≥ 3.00σ (I). The molecular backbone is aza-bicycle [3,2,1] octane containing a chair-like six-membered aza-cycle conformation.