Berberine Ameliorates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats via Activation

• 作 者: Yu-pei ZHANG Yuan-jun DENG Kai
• 机 构: SchoolofTraditionalChineseMedicine,DepartmentofTraditionalChineseMedicine
• 出 处: 当代医学科学(英文)
• 发表日期: 2019年1期
• 关键词: BERBERINE non-alcoholic FATTY liver disease SIRTUIN 3 LIPID METABOLISM
• 基金项目: grants from the National Natural Science Foundation of China(No.81573844 and No.81774165),Medical Research Fund of Guangdong Province(No.A2017363).

This study aimed to verify the effects of berberine(BBR)on the fat metabolism proteins involved in the sirtuin 3(SIRT3)/adenosine 5'-monophosphate(AMP)-activated protein kinase(AMPK)/acetyl-CoA carboxylase(ACC)pathway in the liver tissues of rats with