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目的探讨根治术后提高肿瘤剂量及胸壁照射对Ⅱ期乳癌生存率的影响。材料与方法对比分析１９８０年１月至１９８６年底收治的Ⅱ期乳癌术后行放疗者２４８例（放疗组）与术后未行放疗者１０３例（手术组）。２４８例中ＤＴ≥５０Ｇｙ者５１例，淋巴引流区伴胸壁照射８４例。结果放疗组中ＤＴ≥５０Ｇｙ者与手术组相比，其中腋淋巴转移≥４个者的１０年生存率分别为６５．５％与３３．３％，复发率分别为６．９％与３３．３％，Ｐ＜０．０５。放疗组中淋巴引流区伴胸壁照射８４例与手术组相比，其中腋淋巴转移≥４个者的１０年生存率分别为６１．４％与３３．３％，复发率分别为４．５％与３３．３％，Ｐ＜０．０５。放疗组与手术组锁骨上区转移率分别为２．８％与７．８％，Ｐ＜０．０５。结论术后提高肿瘤剂量达５０Ｇｙ以上，并常规行胸壁放疗，可提高Ⅱ期乳癌生存率。
Objective To investigate the effect of increasing tumor dose and chest wall irradiation on the survival rate of stage Ⅱ breast cancer after radical operation. Materials and Methods Comparative analysis of 248 cases of radiotherapy (radiotherapy group) and 103 cases of radiotherapy (operation group) after operation in the period from January 1980 to the end of 1986. There were 51 cases of 248 patients with DT≥50 Gy and 84 cases of lymphatic drainage with chest wall irradiation. Results In the radiotherapy group, the 10-year survival rates of patients with DT≥50 Gy were 65.5% and 33.3%, respectively, and the recurrence rates were 6.9% and 33%, respectively. 3%, P <0.05. In the radiotherapy group, the 10-year survival rates of 84 patients with lymphatic drainage and chest wall irradiation were 61.4% and 33.3% respectively, and the recurrence rates were 4.5% With 33.3%, P <0.05. The rates of supraclavicular metastases in radiotherapy group and surgery group were 2.8% and 7.8%, respectively, P <0.05. Conclusions Increasing tumor dose to above 50Gy and performing chest wall radiotherapy routinely can improve the survival rate of stage Ⅱ breast cancer.