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目的 探讨循环免疫复合物 (CIC)在乙肝发病机制上的作用。方法 应用聚乙二醇 (PEG)沉淀试验对 1 2 0例乙肝病人和 1 2 0例正常人群进行了循环免疫复合物检测。结果 乙肝病人CIC的阳性率达49 2 % ,正常人群CIC阳性率仅为 1 1 7% ,两者比较差异有非常显著意义 (P <0 0 0 5)。结论 循环免疫复合物在乙肝病理性免疫损害中占有重要地位
Objective To investigate the role of circulating immune complex (CIC) in the pathogenesis of hepatitis B. Methods Polyethylene glycol (PEG) precipitation assay was used to detect circulating immune complexes in 120 patients with hepatitis B and 120 normal controls. Results The positive rate of CIC in patients with hepatitis B was 49.2%, while the positive rate of CIC in normal subjects was only 11.7%. There was significant difference between the two (P <0.05). Conclusion Cyclic immune complexes play an important role in the pathological immune damage of hepatitis B.