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五组初断奶小鼠分别饲喂生育酚（ＶＥ）缺乏，合有Ｖｈ１／３、正常、３倍及２０倍需要量的膳食，８周后观察Ｔ淋巴细胞及亚群的变化。结果表明：补充ＶＥ后，小鼠脾脏指数显著增高，胸腺指数仅略有上升，并提高Ｔ细胞、Ｔ＿Ｈ亚群百分率，降低Ｔ＿ｓ亚群百分率，使Ｔ＿Ｈ／Ｔ＿ｓ比值增高。提示：ＶＥ刺激脾脏细胞增生更为显著，ＶＥ促进Ｔ细胞的成熟、分化。ＶＥ影响免疫反应的作用可能是通过提高Ｔ＿Ｈ／Ｔ＿ｓ比值而进行调节的。除２０倍需要量组外，饲料中ＶＥ重与Ｔ细胞及亚群的提高相关，认为３倍需要量为合适剂量。
Five groups of weaned mice were fed with a diet deficit of tocopherol (VE), Vh1 / 3, normal, 3-fold and 20-fold diet respectively. Changes of T lymphocytes and their subpopulations were observed after 8 weeks. The results showed that the spleen index of mice increased significantly and the thymus index increased only slightly after VE supplementation. The percentage of T_H subsets and T_H subsets increased and T_H / T_s increased. Tip: VE stimulated spleen cell proliferation was more significant, VE promote T cell maturation and differentiation. The effect of VE on the immune response may be mediated by increasing the T_H / T_s ratio. In addition to the 20-fold requirement set, the VE weight in the feed is associated with an increase in T-cells and subsets, accounting for a 3-fold requirement for the appropriate dose.