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目的分析冠状动脉迂曲的检出率及其和冠状动脉粥样硬化(AS)的关系和预后。方法以35例冠状动脉迂曲患者为研究对象,回顾性查阅病史资料和心导管室的数据库;应用Logistic回归法分析年龄、性别、冠心病危险因素、冠状动脉迂曲程度对冠状动脉迂曲近段AS病变的影响;并对患者进行电话或门诊随访。结果本研究中冠状动脉迂曲的检出率为16.43%;通过多因素分析得出年龄、性别、高血压、糖尿病、吸烟史是冠状动脉迂曲近段发生AS病变较强的独立危险因素,冠状动脉迂曲程度也是独立危险因素,但其作用相对较弱,OR值为1.030(95%CI:1.011~1.050);随访期间无患者死亡,无急性心肌梗死发生。结论除了传统的粥样硬化危险因素外,冠状动脉迂曲程度是发生粥样硬化的独立危险因素,其长期预后通常是好的。
Objective To analyze the detection rate of coronary artery tortuosity and its relationship with coronary atherosclerosis (AS) and its prognosis. Methods 35 patients with tortuous coronary artery disease were studied retrospectively with historical data and database of cardiac catheterization. Logistic regression analysis was used to analyze the relationship between age, sex, risk factors of coronary heart disease and coronary artery tortuosity. Of the impact; and patient phone or out-patient follow-up. Results The prevalence of coronary artery tortuosity in this study was 16.43%. Multivariate analysis showed that age, gender, hypertension, diabetes mellitus and smoking history were independent risk factors for AS lesions in the tortuous proximal coronary artery. Coronary artery The degree of tortuosity was also an independent risk factor, but its effect was relatively weaker. The odds ratio was 1.030 (95% CI: 1.011-1.050). No patient died during follow-up and no acute myocardial infarction occurred. Conclusion In addition to the traditional risk factors of atherosclerosis, tortuosity of the coronary artery is an independent risk factor for atherosclerosis. The long-term prognosis is usually good.