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目的探讨单唾液酸神经节苷脂注射液治疗新生儿缺氧缺血性脑病的临床疗效。方法选取2009年5月至2011年5月我院收治的70例缺氧缺血性脑病新生儿患者为研究对象,将其随机地平均分为治疗组和对照组,对照组患儿给予常规治疗,治疗组患儿在常规治疗的基础上辅加单唾液酸神经节苷脂注射液治疗,对比两组患儿的临床效果。结果对照组治疗总有效率为80%,治疗组治疗总有效率为94.3%,两组对比差异明显,具有统计学意义(P<0.05)。结论单唾液酸神经节苷脂注射液治疗新生儿缺氧缺血性脑病,能够控制因缺氧缺血引起的脑水肿,有良好的临床效果,值得临床推广和应用。
Objective To investigate the clinical efficacy of monosialoganglioside injection in the treatment of neonatal hypoxic-ischemic encephalopathy. Methods From May 2009 to May 2011, 70 cases of neonates with hypoxic-ischemic encephalopathy admitted to our hospital were selected as the research object, randomly divided into treatment group and control group, while those in control group were given routine treatment . The treatment group was treated with monosialoganglioside injection on the basis of routine treatment, and the clinical effect was compared between the two groups. Results The total effective rate of the control group was 80%, and the total effective rate of the treatment group was 94.3%. There was significant difference between the two groups (P <0.05). Conclusion Monosialoganglioside injection in neonates with hypoxic-ischemic encephalopathy can control cerebral edema caused by hypoxia and ischemia and has good clinical effect, which is worthy of clinical promotion and application.