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目的分析学校麻疹爆发的因素,为指导今后麻疹学校暴发处理。方法本次调查收集2005~2007学校麻疹爆发病例、并进行流行病学分析;对最近一次麻疹爆发学校学生进行免前免后麻疹IgG抗体水平检测。结果2005~2007年间共发生6起爆发疫情。麻疹爆发的学校均为外来工子弟学校,主要集中发生于3~6月,爆发病例中有免疫史的占22.74%,无免疫史和免疫史不详的分别为27.27%和50.00%。通过对应急接种麻疹疫苗后的血清学监测,麻疹抗体阳性率达96.30%,阳转率达87.50%,已达到免疫保护水平,免后抗体4倍以上增长或抗体阴转阳的有10例,另外13例免疫前高抗体水平者,免后虽无抗体4倍以上增长,但仍保持在高位水平,显示接种麻疹疫苗有良好的免疫效果。结论外来工子女存在着很大的免疫空白,目前我国使用的MV具有较高的免疫成功率,说明了MV应急接种是控制麻疹爆发的有效手段。
Objective To analyze the causes of measles outbreak in schools in order to guide the outbreak of measles schools in the future. Methods The survey collected from 2005 to 2007 school measles outbreak cases, and epidemiological analysis; the latest outbreak of measles school students pre-immune measles IgG antibody levels. Results A total of 6 outbreaks occurred between 2005 and 2007. The outbreaks of measles schools were migrant children schools, mainly occurred in 3 to 6 months, outbreaks of cases of immunization history accounted for 22.74%, no history of immunization and immune history unknown 27.27% and 50.00%. The measles antibody positive rate reached 96.30% and the positive rate reached 87.50% through the serological monitoring of the measles vaccine after emergency vaccination, which reached the level of immune protection. There were 10 cases of antibody increase more than 4 times, The other 13 cases of pre-immune high antibody levels, although no antibody after 4 times more than the increase, but still maintained at a high level, showing a measles vaccination vaccines have a good immune effect. Conclusion There is a large immunization gap among migrant children. At present, the MV used in our country has a high success rate of immunization, indicating that MV vaccination is an effective measure to control the outbreak of measles.