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目的：利用Cerec椅旁计算机辅助设计与制造（ computer aided design and manufacture，CAD／CAM）与功能牙合道（ functionally generated path，FGP）技术修复1例二氧化锆全冠，比较计算机在虚拟牙合架、生物再造、FGP技术下设计牙合面的差异。方法：将16行标准牙体预备后，Cerec 4.4扫描预备体、对牙合牙及咬合状态，并扫描制取的印模（ FGP），在数字化设计中对上述3种模式进行设计，生成3种不同的咬合面。设计FGP二氧化锆全冠后，导出并切削，完成临床试戴、粘接。结果：在CAD中生成的3种模式牙合面存在差异，FGP最佳，生物再造次之，虚拟牙合架最差。FGP技术指导设计可少量调牙合，获得稳定的牙合关系。结论：在椅旁 CAD／CAM 二氧化锆全冠修复中，可推荐使用FGP技术消除牙合干扰。“,”Objective:Combined with Cerec chair?side computer aided design and manufacture(CAD/CAM),to re?pair a case of zirconia full crown and find the differences among the biogeneric reconstruction,virtual articulator,and func?tionally generated path( FGP) technics. Methods:After tooth preparation,Cerec 4. 4 software was used to scan the tooth,the occlusal state,and the impression( FGP) . The three models were designed in the CAD/CAM. Different occlusal surfaces were created,zirconia full crown was milled by using chair?side CAM,tried in and bonded in clinic. Results:There were differ?ences among the three models generated in CAD,but FGP was the best,followed by biological reconstruction,and the virtual model was the worst. FGP technic have made a small amount of clinical bite adjustment,and got a stable relationship. Con?clusion:The best way to use CAD/CAM zirconia crowns in chairs?side to eliminate interference is using FGP technic.