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目的：探讨围产期肺栓塞(PTE)的高危因素、临床特点、诊治预防措施及预后。方法回顾性分析长沙市中心医院住院诊断的12例围产期PTE患者的临床资料。结果围产期PTE患者存在易患因素，以长时间卧床为最常见，其症状和体征是非特异性的。CT肺动脉造影(CTPA)等检查均有助于诊断。早期积极溶栓、抗凝治疗可降低病死率。结论围产期PTE发病率高，易误诊，应早期、积极采取抗凝、溶栓治疗。“,”Objective To discuss the risk factors,clinical features,early diagnosis and treatment of Perinatal pulmonary embolism.Methods The clinical data of 12 patients hospitalized with Perinatal pulmonary embolism in Changsha Central Hospital were reviewed.Results Perinatal pulmonary embolism patients were associated with a number of risks including long time in bed,the most frequent risk factor,and clinical symptoms and signs of PTE were usual y nonspecific.CT pulmonary angiography(CTPA)were helpful to the diagnosis.Early thrombolysis and anticoagulation therapy decreased the case fatality rate.Conclusion The incidence rate of perinatal pulmonary embolism is high,which is easy to misdiagnosis.We should actively take earlier anticoagulation therapy and thrombolytic therapy.