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由于泰国产中国五层龙的80%甲醇提取物具有α-葡糖苷酶抑制活性和抑制蔗糖负荷大鼠血糖升高的作用,故对其活性成分进行了筛选。在分离得到已知活性成分salacinol(6)的同时,还分离到5种新的木栓烷型三萜烯。 中国五层龙的80%甲醇提取物用水-乙酸乙酯分配,得到水溶部分与乙酸乙酯部分。具有α-葡糖苷酶抑制活性的水溶部
Since 80% methanol extracts of S. chinensis produced in Thailand had α-glucosidase inhibitory activity and inhibited the increase of blood glucose in sucrose-loaded rats, their active ingredients were screened. At the same time as the known active ingredient salacinol (6) was isolated, five new xanthanane type triterpenes were also isolated. The 80% methanol extract of S. chinensis was partitioned with water-ethyl acetate to obtain a water soluble portion and an ethyl acetate portion. Water soluble part having α-glucosidase inhibitory activity