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目的探究早产儿脑室周围-脑室内出血术后继发脑积水发生情况及其影响因素,旨在为改善脑室周围-脑室内出血患儿预后提供参考依据。方法选择2010年6月至2014年6月收治的112例脑室周围-脑室内出血早产儿为观察对象,采用自编问卷系统收集患儿临床资料,采用描述性分析和二分类Logistic回归分析探寻脑室周围-脑室内出血早产儿术后继发脑积水情况及其影响因素。结果脑室周围-脑室内出血继发脑积水率为52.68%,男患儿(β=1.73,OR=5.63)、胎龄小(β=1.94,OR=7.05)、出生时窒息(β=1.76,OR=5.81)、脑室周围-脑室内出血分级Ⅲ或Ⅳ(β=1.96,OR=7.12)是早产儿继发脑积水的危险因素(P均<0.01)。结论早产儿脑室周围-脑室内出血继发脑积水率仍较高,其发生受多方面因素影响,应采取针对性的预防干预措施来降低脑室周围-脑室内出血早产儿继发脑积水几率,改善早产儿预后。
Objective To investigate the occurrence of secondary hydrocephalus and its influencing factors in periventricular-ventricular hemorrhage in preterm infants, and to provide reference for improving the prognosis of children with periventricular-intraventricular hemorrhage. Methods One hundred and twelve cases of premature infants with periventricular-ventricular hemorrhage admitted to our hospital from June 2010 to June 2014 were selected. The clinical data of children were collected by self-made questionnaire system. Descriptive analysis and Logistic regression analysis were used to explore the periventricular Secondary hydrocephalus in preterm infants with intraventricular hemorrhage and its influencing factors. Results The rate of hydrocephalus secondary to periventricular - intraventricular hemorrhage was 52.68%. The incidence of asphyxia at birth (β = 1.73, OR = 5.63), gestational age (β = 1.94, OR = 7.05) OR = 5.81). Peripheral - ventricular hemorrhage grade Ⅲ or Ⅳ (β = 1.96, OR = 7.12) were the risk factors of secondary hydrocephalus in preterm infants (all P <0.01). Conclusion Premature infants with periventricular-ventricular hemorrhage secondary hydrocephalus rate is still high, its occurrence is affected by many factors, targeted preventive interventions should be taken to reduce the risk of secondary hydrocephalus in perinatal ventricular hemorrhage preterm children, Improve the prognosis of preterm children.