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脑外伤可引起脑血流灌注异常,后者可进一步加重脑损伤,外伤后早期血流灌注的评价有助于预测预后。CT灌注成像(CTP)能简便快捷地用于创伤性脑损伤(TBI)患者检查,可行性、一致性及可重复性较好。脑挫伤呈低灌注状态,即出现不同程度的脑缺血,这种低灌注既可能是已坏组织、也可能是还能挽救的组织。CTP所见的脑血流灌注与损伤恢复及功能重组相关。与其他脑血流技术相比,CTP优点是检查迅速、可靠性较高、图像分辨率高、所得参数接近PET与氙气CT,缺点是有辐射、覆盖厚度较小及必需注射对比剂。
Traumatic brain injury can cause abnormal cerebral blood flow perfusion, the latter can further aggravate brain injury, early posttraumatic evaluation of blood perfusion is helpful to predict prognosis. CT perfusion imaging (CTP) can be easily and quickly used in patients with traumatic brain injury (TBI) examination, feasibility, consistency and reproducibility is better. Brain contusion was hypoperfusion state, that is, there are different degrees of cerebral ischemia, this hypoperfusion may have been bad tissue, but also may be able to save the organization. Cerebral perfusion seen in CTP is associated with injury recovery and functional remodeling. Compared with other cerebral blood flow techniques, CTP has the advantages of rapid examination, high reliability and high image resolution. The obtained parameters are close to those of PET and xenon CT. The disadvantage is the radiation, the small thickness of the covering and the need of contrast injection.