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肥胖是指脂肪细胞异常增多及细胞内脂质(主要是甘油三酯)的过度沉积。在内的多种疾病的独立风险因素~([1])。自上世纪80年代至今,对肥胖亚群的研究日益增多,出现了代谢正常肥胖(MHO)的概念~([2-5])。MHO亚群存在肥胖的特征,但胰岛素敏感性正常,体脂分布、代谢及炎症谱及减重疗效均与代谢异常的“高危”肥胖有所不同,因此研究者们提出MHO应当在科学研究和临床实践中与高危肥胖
Obesity refers to an abnormal increase in fat cells and excessive deposition of intracellular lipids (mainly triglycerides). The independent risk factors for various diseases, including ~ ([1]). Since the 1980s to the present, research on obesity subgroups has been increasing, and the concept of normal metabolic obesity (MHO) has emerged [2-5]. MHO subpopulation is characterized by obesity, but normal insulin sensitivity, body fat distribution, metabolic and inflammatory profile and weight loss efficacy are different from the “high risk” obesity metabolic abnormalities, so researchers have proposed MHO should be in science Research and clinical practice with high-risk obesity