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[目的]观察止哮方联合西药治疗支气管哮喘疗效。[方法]使用随机平行对照方法,将84例住院患者按病志号抽签简单随机分为两组。对照组42例前3d,泼尼松,15mg/次,1次/d;氨茶碱,0.1g/次,3次/d;3~6d,泼尼松改为5mg/d,6d后停用泼尼松。治疗组42例1~5d,止哮方1号(杏仁、葶苈子、桑白皮、干地龙各15g,炙麻黄、麦冬、苏子、法半夏、瓜蒌皮、白果各10g,乌梅、甘草各6g),1剂/d,水煎至150~200mL,早晚口服;6d后:止哮方2号(党参、熟地、黄芪各30g,茯苓、沙参、白术、胡桃肉各20g,杏仁、法半夏各10g,麦冬15g,五味子10g,甘草5g),1剂/d;水煎150~200mL,早晚口服;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、EOS、CD4+、CD8+、IgE、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈14例,显效24例,有效3例,无效1例,总有效率97.62%。对照组痊愈7例,显效15例,有效11例,无效9例,总有效率78.57%。治疗组疗效优于对照组(P<0.05)。症状积分治疗组有改善(P<0.01),症状积分对照组部分改善(P>0.05,P<0.01),治疗组改善优于对照组(P<0.05,P<0.01)。[结论]止哮方联合西药治疗支气管哮喘效果显著,值得推广。
[Objective] To observe the curative effect of anti-asthma combined western medicine on bronchial asthma. [Methods] Using randomized parallel control method, 84 inpatients were randomly divided into two groups randomly according to the patient’s lot number. The control group 42 patients before the first 3d, prednisone, 15mg / times, 1 / d; aminophylline, 0.1g / times, 3 times / d; 3 ~ 6d, prednisone to 5mg / d, 6d after stopping With prednisone. Treatment group, 42 cases of 1 ~ 5d, Zhiguo Fang 1 (almonds, razor clam, Morus alba, dried earthworm each 15g, burdock yellow, Ophiopogon, Suzi, Pinellia, melon skin, ginkgo 10g , Ebony, licorice each 6g), 1 / d, decoction to 150 ~ 200mL, sooner or later oral; 6d after: stop the asthma on the 2nd (Codonopsis, Rehmannia, Astragalus 30g, Poria, Radix, Atractylodes, Walnut 20g, almonds, French Pinellia each 10g, Ophiopogon 15g, Schisandra 10g, licorice 5g), 1 / d; decoction 150 ~ 200mL, morning and evening oral; Western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observed clinical symptoms, EOS, CD4 +, CD8 +, IgE, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] In the treatment group, 14 cases were cured, 24 cases were markedly effective, 3 cases were effective, 1 case was ineffective and the total effective rate was 97.62%. The control group recovered in 7 cases, markedly effective in 15 cases, effective in 11 cases, ineffective in 9 cases, the total effective rate was 78.57%. The treatment group was better than the control group (P <0.05). The score of the symptom improvement group was improved (P <0.01), symptom score control group was partially improved (P> 0.05, P <0.01), treatment group improved better than the control group (P <0.05, P <0.01). [Conclusion] Asthma combined with Western medicine in treating bronchial asthma is effective and worth promoting.