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目的 探讨结、直肠癌肝转移的外科治疗。方法 对１９９３ 年１ 月至１９９９ 年１ 月的１９ 例结、直肠癌肝转移患者行外科治疗。其中６ 例同期切除，１０ 例分期切除，１ 例肝动脉结扎加无水乙醇注射，２ 例通过肝动脉结扎加化学药物治疗（化疗） 泵灌注化疗而获得二期手术切除机会。手术方式行肝不规则楔形切除１６ 例，左半肝切除２ 例。结果 术后１、３、５ 年生存率分别为８９％ 、５８％ 、２１％ 。６ 例同期肝切除者平均生存期２３ 个月，１０ 例分期肝切除者的平均生存期为３２ 个月。结论 掌握手术时机和适应证，积极进行肝动脉灌注化疗，提高手术切除成功率是提高存活率的关键。
Objective To investigate the surgical treatment of liver metastasis of colorectal cancer. Methods From January 1993 to January 1999, 19 patients with colorectal cancer and liver metastases underwent surgical treatment. Among them, 6 cases underwent simultaneous resection, 10 cases underwent staged resection, 1 case of hepatic artery ligation plus ethanol injection, and 2 cases received hepatic artery ligation plus chemotherapy (chemotherapy) pump perfusion chemotherapy to obtain secondary surgical resection. Hepatic irregular wedge resection was performed in 16 cases and left hemihepatectomy in 2 cases. Results The 1-, 3-, and 5-year survival rates were 89%, 58%, and 21%, respectively. The average survival time of 6 patients with hepatic resection was 23 months, and the average survival time of 10 patients with staged hepatectomy was 32 months. Conclusions It is the key to improve the survival rate to master the timing of operation and indications, actively perform hepatic arterial infusion chemotherapy, and improve the success rate of surgical resection.