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目的观察呼出气一氧化氮(FeNO)在老年哮喘诊治中的变化特点。方法选取医院诊治的老年哮喘患者(哮喘组)42例,选取同期健康体检者(体检组)42例,比较2组患者FeNO与肺功能测定结果。结果哮喘组在治疗前FeNO明显高于健康组,FEV1%明显低于健康组,差异均有统计学意义(P<0.01)。哮喘组治疗2周及1个月后FeNO较治疗前明显下降,FEV1%较治疗前改善显著,差异均有统计学意义(P<0.01)。结论 FeNO检测对老年哮喘诊治有重要意义。
Objective To observe the changes of exhaled nitric oxide (FeNO) in the diagnosis and treatment of senile asthma. Methods Forty-two elderly patients with asthma (asthma group) were enrolled in this study. Forty-two healthy subjects (physical examination group) were enrolled in this study. FeNO and pulmonary function test results were compared between the two groups. Results The FeNO of asthma group was significantly higher than that of healthy group before treatment, and the FEV1% was significantly lower than that of healthy group (P <0.01). The FeNO decreased obviously in the asthma group two weeks and one month after treatment, and the FEV1% improved significantly compared with that before the treatment (P <0.01). Conclusion The detection of FeNO is of great significance in diagnosis and treatment of senile asthma.