Preparation and preliminary evaluation of [^55Co]（II）vancomycin

• 作 者: Amir Reza JALILIAN Yousef YARI
• 机 构: NuclearMedicineResearchGroup
• 出 处: 核技术：英文版
• 发表日期: 2008年6期
• 关键词: 钴-55 万古霉素 医用回旋加速器 放射性同位素示踪 生物剂量学 Cobalt-55 Vancomycin Medical cyclotron Radio
• 基金项目: Supported partly by IAEA/IAEO research grant for cyclotron production of Co-57.AcknowledgementsWe would like also thank Ms. S. Moradkhani and Mr. S. Daneshvari for conducting animal tests.

Co-55 (t1/2=17.53 h) was produced by 150 μA irradiation of a natural nickel target using 15 MeV protons. It was separated from the irradiated target material by two ion exchange chromatography steps with a radiochemical yield of >95% and was used for t