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目的：观察、探讨真菌性角膜炎联合药物治疗的临床治疗效果。方法将30例临床确诊的真菌性角膜炎病患随机分为两组，每组15例。治疗组采用特比萘酚和氟康唑联合治疗，对照组则单独给予氟康唑进行治疗。观察、记录两组病患的治疗效果，并通过相应治愈率、治疗有效率和病程长短来分析评价两种治疗方案的疗效。结果采用特比萘酚和氟康唑联合疗法的治疗组的治愈率为80.0%，有效率为93.3%，且平均治愈周期为20.5天（P<0.05）；单独给予氟康唑治疗的对照组的治愈率仅为33.3%，有效率为73.3%，而且平均治愈周期为22.7天（P<0.05）。结论特比萘酚联合氟康唑治疗真菌性角膜炎疗效确切，其治愈率较单独给予氟康唑高出46.7%，有效率高出20.0%，而且平均治愈周期也较后者短2.2天（P<0.05），值得临床推广。“,”Objective To observe and explore the combination use of terbinafine phenol and fluconazole on fungal keratitis. Methods 30 cases of fungal keratitis patients hospitalized in our hospital were randomly divided into two groups, 15 cases in each group. The group A was treated with the combination use of terbinafine phenol and fluconazole, while group B was treated with fluconazole alone. Observe and record every patient’s condition and treatment to get the cure rate, efficient and cure cycle of each group, so as to evaluate corresponding treatment. Results The cure rate, efficient and cure cycle of group A is 80.0%, 93.3% and 20.5 days, respectively (P<0.05); while 33.3%, 73.3% and 22.7 days, respectively (P<0.05) in group B. Conclusions The combination use of terbinafine phenol and fluconazole to treat fungal keratitis is significantly better than the use of fluconazole alone, with higher cure rate, efficient and shorter cure cycle.