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用双盲、随机、无效对照研究840例60岁以上高血压患者的抗高血压治疗,表明心血管病治疗组病死率显著低于安慰剂组。本文分析其抗高血压治疗的副作用。方法:坐位血压为21.3～31.8/12.0～15.8千帕的60岁以上患者随机分为氨苯蝶啶+氢氯噻嗪组416例;安慰剂组424例,当血压持续高水平时均加用甲基多巴。进入研究后相关疾病和症状每年记录1次,
A double-blind, randomized, placebo-controlled study of antihypertensive treatment in 840 hypertensive patients over the age of 60 showed that mortality was significantly lower in the cardiovascular-disease arm than in the placebo arm. This article analyzes the side effects of antihypertensive treatment. Methods: A total of 416 patients aged 60 years or older with sitting blood pressure of 21.3-31.8 / 12.0-15.8 kPa were randomized to receive triamterene + hydrochlorothiazide (416 cases). Patients in the placebo group (424 cases) were given more methyl bar. After entering the study related diseases and symptoms recorded once a year,