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近年来,对有关调节造血的各种机能间相互作用的关系,已经有了广泛的研究,而且已经了解到有好些种体液因素可以影响造血细胞的生长和分化。然而,总的来说,这些造血的体液调节因子都是作用于已经定向到一个特定的分化途径的造血干细胞(HSC)。但是决定未定向的、多能HSC功能作用机制间的相互关系仍有待于进一步阐明。一些可以得到的证据曾提示多能HSC的功能是通过造血器官中局部或微环境因素在近距离范围内的相互作
In recent years, extensive research has been conducted on the relationship between various functions of regulating hematopoiesis, and it has been learned that there are several kinds of humoral factors that can affect the growth and differentiation of hematopoietic cells. However, in general, these hematopoietic humoral regulators act on hematopoietic stem cells (HSCs) that have been targeted to a particular differentiation pathway. However, the interrelationship between non-oriented and multifunctional HSC functional mechanisms remains to be elucidated. Some of the available evidence suggests that the function of pluripotent HSCs is through the interaction of local or microenvironmental factors in hematopoietic organs at close range