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目的通过对21例艾滋病(AIDS)合并肺孢子菌肺炎(PCP)病例分析,探讨艾滋病合并肺孢子菌肺炎患者临床特点,提高对该病的认识,为临床诊断和治疗提供参考。方法对2005年1月至2010年12月收治的21例AIDS并发PCP患者的临床资料进行回顾性分析。结果 21例AIDS合并PCP患者,CD 4+T淋巴细胞计数均<200cell/mm3)(8～158cell/mm3),15例<50cell/mm3;恶化及死亡3例,均为重症或出现严重并发症者。结论 PCP的临床表现以呼吸道症状为主,而肺部体征较轻,症状与体征不一致的临床表现为该病的特点之一;胸部x线主要表现为间质性改变;CD4+细胞计数小于50cell/mm3为PCP发病的高危因素;PCP的早期诊断、及时治疗对疾病转归具有十分重要的意义。
Objective To investigate the clinical features of 21 cases of AIDS complicated with pneumosporidium pneumonia (PCP) and to explore the clinical features of patients with pneumococcal pneumonia and improve their understanding of the disease, so as to provide reference for clinical diagnosis and treatment. Methods The clinical data of 21 AIDS patients with PCP admitted from January 2005 to December 2010 were analyzed retrospectively. Results 21 AIDS patients with PCP had CD 4 + T lymphocyte counts of <200cell / mm3 (8 ~ 158cell / mm3) and 15 cases of <50cell / mm3. There were 3 cases of exacerbation and death, By. Conclusions The clinical manifestations of PCP are mainly respiratory symptoms, while the signs of lungs are mild. The clinical manifestations of inconsistent symptoms and signs are one of the characteristics of the disease. The chest x-ray mainly shows interstitial changes. The CD4 + cell count is less than 50cell / mm3 risk factors for the pathogenesis of PCP; PCP early diagnosis and timely treatment of disease prognosis is of great significance.