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组胺H_2受体拮抗剂的临床应用使消化性溃疡的内科治疗有了令人鼓舞的发展。继西咪替丁之后雷尼替丁是运用最广的一种。该药我国已能生产,且日趋广泛地在国内应用。雷尼替丁的作用较西咪替丁强4～8倍, 副作用也较小。一般认为雷尼替丁的副作用发生率低于3%,较常见的有头痛、头晕、疲倦、不适、恶心、便秘、轻泻及皮疹等,但症状均轻微,不影响继续用药,且许多患者在继续用药过程中上述症状可自然缓解,仅少数病例被迫中断治疗。随着治疗病例的增多,一些少见副作用相继发现并见报道。有些副作用较为严重,
The clinical application of histamine H 2 receptor antagonists has led to an encouraging development in the medical treatment of peptic ulcer disease. After cimetidine ranitidine is the most widely used. The drug has been able to produce our country, and is increasingly widely used in the country. Ranitidine than cimetidine strong 4 to 8 times, side effects are also small. The incidence of side effects of ranitidine is generally considered to be less than 3%, with headache, dizziness, tiredness, discomfort, nausea, constipation, laxation and rash more common, but the symptoms are mild and do not affect the continuation of medication, and many patients In the process of continuous medication of the above symptoms can be naturally alleviated, only a few cases were forced to interrupt treatment. With the increase of treatment cases, some rare side effects have been found and reported. Some side effects are more serious,