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妊娠期为一种超敏反应的预备阶段,所以当患病毒性肝炎时,则易为重症肝炎;而一旦重症肝炎合并妊娠时,则发生DIC的机会极大。一、重症肝炎合并妊娠并发DIC的原因当肝炎发生之后,肝细胞受损严重,则凝血因子的产生减少,其中以第Ⅱ、Ⅶ、Ⅸ、Ⅹ等因子最易减少,特别是第Ⅶ因子;而第Ⅰ因子(纤维蛋白原)的产生也降低。另外,抗凝血酶Ⅲ(ATⅢ)及抗纤溶酶在此等情况下也可显著减少。另外由于肝细胞受损严重可释放出大量凝血活酶样物质,终导致DIC的发生,又致继发性纤维蛋白溶
Pregnancy is a preparatory stage of hypersensitivity, so when suffering from viral hepatitis, it is easy for severe hepatitis; and once severe hepatitis with pregnancy, the chance of DIC is extremely great. First, the causes of severe hepatitis complicated by pregnancy complicated with DIC When hepatitis occurs, the serious damage to liver cells, the reduction of clotting factor, of which Ⅱ, Ⅶ, Ⅸ, Ⅹ and other factors most likely to reduce, especially the Ⅶ factor; The production of factor I (fibrinogen) is also reduced. In addition, antithrombin Ⅲ (AT Ⅲ) and anti-plasmin in these circumstances can be significantly reduced. In addition due to serious damage to liver cells can release a large number of thromboplastin-like substances, eventually leading to the occurrence of DIC, and secondary fibrinolysis