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颅内生殖细胞瘤对放射高度敏感,50Gy的剂量就能达到90%以上的治愈率,尽管该剂量对脑组织而言是安全的,但仍可导致认知和垂体功能障碍等严重并发症。鉴于与它有一致组织学特征的睾丸精原细胞瘤却能在25~35Gy水平获得治愈,为此,在1985-1995年间作者作了按肿瘤体积选择治疗剂量的前瞻性研究,其结果如下。 该组病例共38例,男女比例31∶7,中位年龄17岁(9~32岁)。21例有组织学报道,17例按年龄、肿
Intracranial germinomas are highly radiation-sensitive and can achieve a cure rate of 90% or more at a dose of 50 Gy, although this dose is safe for brain tissue but can still cause serious complications such as cognitive and pituitary dysfunction. In view of its consistent histological features of testicular seminoma can be cured at 25 ~ 35Gy level, therefore, in 1985-1995 the author made a dose-dependent treatment of tumor volume prospective study, the results are as follows. The group of 38 patients, male to female ratio of 31: 7, the median age of 17 years (9 to 32 years old). 21 cases of histological reports, 17 cases by age, swollen