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目前虽已明确肾功能损害患者的血清β_2-微球蛋白(β_2-MG)浓度升高,但有关肾脏对β_2-MG的处理和组织学改变之间的关系报道很少。Suxuki等阐述了肾脏病患者肾脏β_2-MG免疫组织学定位和肾脏损害或肾功能损害之间的关系。材料和方法:总共119例肾脏病患者,年龄9～72岁,肾活检标本经光镜、电镜和免疫荧光检查而确诊为各种肾脏病。应用免疫荧光法检查肾脏是否有β_2-MG沉积,且为了弄清β_2-MG沉积的精确部
Although the serum concentration of β_2-microglobulin (β_2-MG) in patients with impaired renal function is clearly elevated, there are few reports on the relationship between β_2-MG treatment and histological changes in the kidney. Suxuki et al. Describe the relationship between renal β_2-MG immunohistopathology and renal or renal dysfunction in patients with kidney disease. MATERIALS AND METHODS: A total of 119 patients with nephrotic disease, aged 9 to 72 years, were diagnosed with various renal diseases by light microscopy, electron microscopy and immunofluorescence. Immunofluorescence was used to examine whether there was deposition of β_2-MG in the kidneys, and in order to clarify the exact part of β_2-MG deposition