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目的探讨蒙脱石散剂保留灌肠治疗小儿腹泻的临床疗效。方法选取2005年9月至2009年12月我院门诊收治的60例患儿,随机分成对照组和观察组,每组各30例。对照组给予抗感染、补液、对症支持治疗、口服蒙脱石散剂,肠道微生态剂、对证治疗;观察组在对照组的基础上采用蒙脱石散剂保留灌肠治疗,观察两组患儿治疗效果及副作用发生情况。结果观察组总有效率90%,对照组总有效率79%,两组总有效率经统计学分析,差异具有统计学意义(P<0.05)。两组治疗过程中均未见明显不良反应发生。结论蒙脱石保留灌肠治疗小儿腹泻疗效高,副作用少,减少患儿并发症,临床上使用安全,且价廉易接受,值得临床推广应用。
Objective To investigate the clinical efficacy of montmorillonite powder retention enema in children with diarrhea. Methods Sixty children admitted to our hospital from September 2005 to December 2009 were randomly divided into control group and observation group, with 30 cases in each group. The control group was given anti-infective, rehydration, symptomatic and supportive treatment, oral montmorillonite powder, intestinal microecological agent and the treatment of syndrome. The observation group was treated with montmorillonite powder retention enema on the basis of the control group. Therapeutic effects and side effects occurred. Results The total effective rate was 90% in the observation group and 79% in the control group. The total effective rate in the two groups was statistically analyzed (P <0.05). No significant adverse reactions occurred in both groups during the course of treatment. Conclusion Montmorillonite retention enema for children with diarrhea, high efficacy, fewer side effects, reduce complications in children, the safe use of the clinic, and affordable easy to accept, worthy of clinical application.