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目的：探讨雷尼替丁、阿莫西林及胶体果胶铋合用治疗十二指肠溃疡和根除幽门螺杆菌的疗效。方法：５４例经胃镜检查确诊为十二指肠球部溃疡并经尿素酶及聚合酶链反应（ＰＣＲ）证实为幽门螺杆菌（ＨＰ）感染的病人。给雷尼替丁１５０ｍｇ，ｐｏ，ｂｉｄ，阿莫西林５００ｍｇ，ｐｏ，ｔｉｄ，胶体果胶铋１２０ｍｇ，ｐｏ，ｑｉｄ。服２ｗｋ后停阿莫西林及胶体果胶铋，继续服用雷尼替丁１５０ｍｇ，ｑｎ，１ｍｏ。停药１ｍｏ后复查胃镜并作ＨＰ检查，结果：溃疡愈合率８７％，ＨＰ根除率８３％。结论：本组研究联合用药取得较为满意的结果，符合价廉、高效的治疗目的。
Objective: To investigate the efficacy of combination of ranitidine, amoxicillin and colloidal bismuth pectin in the treatment of duodenal ulcer and eradication of Helicobacter pylori. Methods: Fifty-four patients with duodenal ulcer diagnosed by gastroscopy were confirmed as H. pylori infection by urease and polymerase chain reaction (PCR). To ranitidine 150mg, po, bid, amoxicillin 500mg, po, tid, colloidal bismuth pectin 120mg, po, qid. After stopping 2wk amoxicillin and colloidal bismuth pectin, continue to take ranitidine 150mg, qn, 1mo. Gastroenterology was performed after 1 month of withdrawal and HP examination. The results showed that the ulcer healing rate was 87% and the HP eradication rate was 83%. Conclusion: This study combined with the drug to obtain more satisfactory results, in line with inexpensive, efficient therapeutic purposes.