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目的探讨无肝素冠脉造影的安全性及可行性。方法选择单纯行冠脉造影的患者182例,分为肝素组和无肝素组,分析两组患者APTT随时间的变化规律,并对所有患者的临床资料进行总结。结果共收集患者182例,实验组98例,男性60例,女性38例,平均年龄55.98±10.11岁;对照组84例,男性51例,女性33例,平均年龄56.67±11.41岁,平均手术时间:实验组17.5±2.21min,对照组18.2±2.42min,APTT结果有统计学差异,两组均无严重并发症发生。结论无肝素冠脉造影缩短了患者卧床时间,节约了医疗资源,无血栓栓塞现象发生,临床安全可行。
Objective To investigate the safety and feasibility of heparin-free coronary angiography. Methods A total of 182 patients with simple coronary angiography were divided into heparin group and non-heparin group. The changes of APTT in both groups over time were analyzed. The clinical data of all patients were summarized. Results A total of 182 patients were collected, the experimental group of 98 cases, 60 males and 38 females, mean age 55.98 ± 10.11 years; control group of 84 patients, 51 males and 33 females, mean age 56.67 ± 11.41 years, mean operative time : Experimental group 17.5 ± 2.21min, control group 18.2 ± 2.42min, APTT results were statistically significant, no serious complications occurred in both groups. Conclusion Heparin-free coronary angiography shortens the patient’s bed rest time, saves medical resources, and does not cause thromboembolism. It is safe and feasible in clinical practice.