Clinical analysis of seventy-two patients with chronic thromboembolic pulmonary hypertension

• 作 者: 程显声 李瑛 李清 高莹 马秀平 李亚辉
• 机 构: FuwaiHospital，CAMS＆PUMC，Beijing100037，China,ShenzhenRed-CrossHospital,FuwaiHospital，CAMS＆PUMC，Beijin
• 出 处: 中华内科杂志
• 发表日期: 1998年37期
• 关键词: Thromboembolism Hypertension pulmonary

Objective　To improve the identification of chronic thromboembolic pulmonary hypertension. Methods　We restrospectively analysed the clinical data of 72 patients with chronic thromboembolic pulmonary hypertension （CTEPH）.Results　Arterial blood gases showed a decrease in PaO2 and PaCO2, and an increase in P（A-a） O2. There were 80.3％ of unsymmetrical pulmonary hyperlucencies on chest radiograph and 76.4％ of right ventricular hypertrophy on electrocardiograph, 92.5％ and 97.1％ of right atrial and right ventricular enlargement, respectively. 11.1％ of pericardial effusion was noted on echocardiograph, and Doppler examination showed a rise in pulmonary arterial pressure in 98.5％ of patients. The mean pulmonary arterial pressure was 6.50±1.80 kPa （48.75±13.50 mmHg） by right cardiac catheterization. The incidences of pulmonary embolism were 100％ both on pulmonary angiography and on radionuclide lung perfusion scan. 43.1％ of patients had a history of deep venous disorders and 75.0％ showed positive findings by radionuclide venography in the lower extremities. The diagnosis was not made before hospitalization in 90.3％. Conclusion　The understanding of clinical manifestations and laboratory findings of CTEPH is important to improve the diagnosis of CTEPH.