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本文报道了凤台县1982~1993年肾综合征出血热人间疫情、兽间疫情监测及控制效果。自1957年治淮水利工程某工段发生首例病人以来,病例逐年增多,疫区逐渐扩大。1959~1993年共发病6924例,死亡141例,年均发病率由60年代的8.28/10万上升至80年代的80.64/10万,90年代前3年发病率为67.75/10万,病死率由1959年的40%、60年代的6.47%、80年代的1.59%降至90年代(前3年)的0.56%。疫区由初发的河湾湖洼地区逐渐扩大,现已波及全县所有乡镇。30多年来本病发生过4次较大流行,重疫区相对稳定,发病呈季节性高峰,以青壮年农民居多,男性略高于女性。患者恢复期血清抗体阳性率95.42%。健康人群隐性感染率1982~1990年为1.79%;而1991~1993年则为4.73%。黑线姬鼠和褐家鼠分别是野外及居民区优势种,构成比分别占80.49%和51.49%,其密度亦较高,与HFRS发病相关,并从黑线姬鼠和褐家鼠肺中检出HFRS病毒抗原。
This article reports the epidemiological and epidemic control of hemorrhagic fever with renal syndrome in Fengtai County from 1982 to 1993. Since the first case of a section of the Huai River water conservancy project in 1957, the number of cases has increased year by year, and the epidemic area has gradually expanded. In 1959 ~ 1993 a total of 6924 cases were reported with 141 deaths, the average annual incidence increased from 8.28 / 100 in the 1960s to 80.64 / 100000 in the 1980s, and the incidence was 67.75 / 100 000 in the first three years of the 1990s. The mortality rate From 40% in 1959, 6.77% in the 1960s, and 1.59% in the 1980s to 0.56% in the 1990s (the first three years). The epidemic area from the beginning of the Bay Lake depression gradually expanded, has now affected all the township of the county. Over the past 30 years, the disease has witnessed 4 major epidemics, with relatively stable epidemic-prone areas and seasonal peak incidence. Most young and middle-aged peasants are male, slightly higher than women. The serum antibody positive rate of convalescent patients was 95.42%. The prevalence of latent infection in healthy population was 1.79% in 1982 ~ 1990, compared with 4.73% in 1991 ~ 1993. Apodemus agrarius and Rattus norvegicus were the dominant species in the wild and residential areas respectively, accounting for 80.49% and 51.49% of the total respectively, with higher density and higher incidence of HFRS. HFRS virus antigen was detected.