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目的:分析培美曲塞与那奈达铂联用对晚期恶性肿瘤患者的临床疗效及护理。方法:选取肿瘤科2014年1月—2014年6月间收治的晚期恶性肿瘤患者12例作为观察对象,其中5例给予培美曲赛单用治疗,为单一用药组;7例患者给予培美曲塞与奈达铂联用治疗,为联合用药组;观察两组患者用药后不良反应的发生情况,并采取有效的护理干预措施。结果:用药过程对患者出现的胃肠道反应、皮肤毒性反应、肾脏和血液毒性反应进行检测,对症治疗,所有患者均安全渡过4个周期性的治疗。结论:培美曲塞与奈达铂联用治疗晚期恶性肿瘤患者具有较好的疗效,且不良反应的发生率较少,通过积极有效地护理干预措施,促进了患者安全有效的治疗,改善生存质量,延长生存时间。
Objective: To analyze the clinical effect and nursing of pemetrexed in combination with naradag in patients with advanced malignancies. Methods: Twelve patients with advanced malignant tumors who were admitted to Department of Oncology from January 2014 to June 2014 were selected as the observation subjects. Five patients were treated with pemetrexed alone for the single treatment group. Seven patients were given pemetrexed Qu Qa combined with nedaplatin treatment for the combination group; observed two groups of patients after treatment of adverse reactions, and take effective nursing interventions. Results: During the course of medication, gastrointestinal tract reactions, skin toxicity, renal and hematologic toxicity were detected and symptomatic treatment was performed in all patients. All patients were safely treated with 4 cycles of treatment. Conclusions: Pemetrexed combined with nedaplatin has a good curative effect in the treatment of advanced malignant tumors, and the incidence of adverse reactions is less. Through active and effective nursing interventions, it is possible to promote safe and effective treatment and improve survival of patients Quality, prolong survival time.