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目的探讨疑似恶性肿瘤的肺外结核使用γ干扰素实验的诊断的临床功效。方法选取2014-03-2016-05成都市公共卫生临床医疗中心就诊可疑肺外结核患者210例,对其进行T-SPOT实验,判断γ-干扰素释放试验在临床中的诊断作用。结果 210例患者确诊肺外结核135例,排除60例,15例不能排除是否感染结核杆菌,γ-干扰素释放试验灵敏度84%,特异性53%。结论γ-干扰素释放试验灵敏度高、特异性强,对肺外结核诊断具有一定的辅助功效。
Objective To investigate the clinical efficacy of the diagnosis of extrapulmonary tuberculosis in patients with suspected malignancy using IFN-γ. Methods Totally 210 suspected pulmonary TB patients were treated in Chengdu Public Health Clinical Medical Center from March 2014 to May 2016, T-SPOT was performed to determine the diagnostic value of interferon-gamma release in clinical practice. Results Of the 210 patients, 135 cases were diagnosed with extrapulmonary tuberculosis and 60 cases were excluded. Fifteen cases could not rule out the possibility of infection with Mycobacterium tuberculosis. The sensitivity and specificity of IFN-γ release assay were 84% and 53% respectively. Conclusion γ-interferon release test with high sensitivity and specificity of the extra pulmonary pulmonary tuberculosis diagnosis has some auxiliary effect.