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为了探讨Ｅｐｓｔｅｉｎ－Ｂａｒ病毒在喉鳞癌细胞中的表达情况，对９０例喉鳞癌组织进行了Ｅｐ－ｓｔｅｉｎ－Ｂａｒｒ病毒潜伏膜蛋白（ＥＢＶ－ＬＭＰ－１）的检测，结果显示，ＬＭＰ－１主要定位于细胞膜和细胞浆内，９０例喉鳞癌中ＬＭＰ－１阳性者４１例，阳性检出率为４５．５％，其中低分化鳞癌阳性率为４４％（１２／２７），中分化鳞癌为５２％（２５／４８），高分化鳞癌为２６．６％（４／１５）。提示，ＥＢ病毒不仅存在于低分化喉鳞癌中，也存在于高分化鳞癌中，喉癌的发生可能与ＥＢ病毒感染有关。
In order to investigate the expression of Epstein-Bar virus in laryngeal squamous cell carcinoma, we detected the expression of Ep-stein-Barr virus latent membrane protein (EBV-LMP-1) in 90 cases of laryngeal squamous cell carcinoma. The results showed that LMP-1 Mainly located in the cell membrane and cytoplasm. Of the 90 laryngeal squamous cell carcinomas, 41 were positive for LMP-1, the positive rate was 45.5%. The positive rate of poorly differentiated squamous cell carcinoma was 44% (12/27) Differentiated squamous cell carcinoma was 52% (25/48), well-differentiated squamous cell carcinoma was 26.6% (4/15). Tip, EB virus not only exists in poorly differentiated laryngeal squamous cell carcinoma, also exists in well-differentiated squamous cell carcinoma, laryngeal cancer may be associated with Epstein-Barr virus infection.