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近年发现体内前列腺素影响分娩过程,孕妇进行阴道检查或胎膜剥离的刺激可使血中前列腺素(PG)成倍增长,外源性PG可激发体内PG分泌。作者推荐阴道放置加甲基纤维素及水配成凝胶剂的PGF_2α50毫克,可有效地用于晚期妊娠引产。经对平均27岁,妊娠35～41周,单胎,头先露,无疤痕子宫,拟用扩张宫颈剥离胎膜进行手术引产孕妇80名,随机等分两组,在计划引产前夕,用注射器及柔软胶管分别将含安慰剂及PGF2α的凝胶推入阴道后穹窿,并嘱卧床1小时,次晨8时作对照观察。
In recent years, the body found that prostaglandins affect the delivery process, pregnant women vaginal examination or membrane stripping stimulation can make blood prostaglandin (PG) doubled, exogenous PG can stimulate in vivo PG secretion. The authors recommend pessary with methylcellulose and water to form a gel agent PGF_2α50 mg, can be effectively used for induction of late pregnancy. After an average of 27 years of gestation, 35 to 41 weeks of gestation, single fetus, first dew, no scar uterus, 80 cases of induced abortion were enrolled in this study. Randomly divided into two groups, on the eve of planned induction of labor, And soft tube with placebo and PGF2α gel were pushed into the vaginal fornix, and told the bed for 1 hour, next morning at 8 o’clock for the control observation.