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目的探讨2013年佛山市顺德龙江地区登革热病例的临床及实验室特征,为临床诊治提供依据。方法对龙江地区2013年新发25例登革热患者临床与实验室资料进行回顾性分析。结果登革热患者主要临床表现为发热(100%)、头痛(76%)、肌痛(76%)、皮疹或出血点(60%)。分别有48%和24%的患者出现白细胞计数减少与血小板计数下降。20%的患者丙氨酸转氨酶水平升高,64%的患者出现天冬氨酸转氨酶升高,男性高于女性。同时,有48%的患者乳酸脱氢酶升高和20%的患者出现肌酸磷酸肌酶升高。结论佛山龙江地区本次登革热为多点散发的本地疫情,患者临床症状较轻,部分患者出现肝脏损害及心肌损伤,经积极治疗临床恢复较好。
Objective To investigate the clinical and laboratory features of dengue fever cases in Longjiang area of Shunde, Foshan City in 2013, and provide the basis for clinical diagnosis and treatment. Methods The clinical and laboratory data of 25 cases of dengue fever newly diagnosed in Longjiang district in 2013 were analyzed retrospectively. Results The main clinical manifestations of dengue fever were fever (100%), headache (76%), myalgia (76%), rash or bleeding point (60%). In 48% and 24% of patients, respectively, the white blood cell count decreased and the platelet count decreased. Alanine aminotransferase levels were elevated in 20% of patients, aspartate aminotransferase in 64% of patients, and higher in males than in females. Concurrently, lactate dehydrogenase was elevated in 48% of patients and creatine phosphokinase in 20% of patients. Conclusion The dengue fever in Longjiang area of Foshan City is a local epidemic with multi-point distribution. The clinical symptoms of the patients were mild. Some patients showed liver damage and myocardial injury, and the active recovery from clinical treatment was better.