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葡萄胎与胎儿同时并存的双胎妊娠发生率估计为22000~100000次妊娠中有一次。1965年以来,波士顿的新英格兰滋养细胞疾病中心治疗了9例这类患者,其中1例为部分性葡萄胎与正常胎盘和胎儿同时并存,另外8例为完全性葡萄胎与胎儿同时并存。将此8例以及文献报道的14例完全性葡萄胎与胎儿同时并存的多胎妊娠同71例完全性葡萄胎单胎妊娠的患者进行了比较,完全性葡萄胎与胎儿同时并存的多胎妊娠的患者的临床症状与完全性葡萄胎单胎
The incidence of twin pregnancies with simultaneous hydatidiform mole and fetus is estimated to be between 22,000 and 100,000 pregnancies. Nineteen such patients were treated by the New England Trophoblastic Disease Center in Boston since 1965, with one case of partial hydatidiform mole coexisting with normal placenta and fetus, and the other 8 cases of complete hydatidiform mole coexisting with the fetus. The 8 cases and 14 cases of complete hydatidiform moles and fetuses co-exist in the literature were compared with 71 cases of complete hydatidiform mole single pregnancy. Patients with multiple hydatidiform mole who had complete hydatidiform mole and fetus concurrently Clinical symptoms and complete hydatidiform mole