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很久以来,人们就想获得一种仅对某一特异性抗原的单一抗体。1975年Kohler和Milstein首光报导了杂交瘤技术,为制备单克隆体提供了新的方法。此法的基本原理是将免疫的脾淋巴细胞
For a long time, people wanted to obtain a single antibody against only one specific antigen. The first light of Kohler and Milstein in 1975 reported hybridoma technology, which provided a new method for the preparation of monoclonal antibodies. The basic principle of this method is to immunize spleen lymphocytes