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GATA-1是一种红系特异性转录调节因子,其结合基序广泛存在于红系特异表达基因的顺式调节元件中;GATA-1具有锌指结构;能反式激活携带其结合基序的报告基因,在红系细胞分化发育中起重要作用。
GATA-1 is a erythroid-specific transcriptional regulator whose binding motif is widely found in the cis-regulatory elements of erythroid-specifically expressed genes; GATA-1 has a zinc finger structure; transactivation of its transmembrane motif The reporter gene plays an important role in erythroid differentiation.