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目的探讨肌钙蛋白Ⅰ(cTnI)的测定在急性心肌梗塞(AMI)早期诊断中的临床价值。方法定性测定29例AMI患者在入院后不同时间的肌钙蛋白Ⅰ,同时测其肌酸激酶(CK),肌酸激酶同功酶(CK-MB),乳酸脱氢酶(LDH)心肌酶学。对其检测结果进行比较。结果急性心肌梗塞患者发病在3~6小时,血清肌钙蛋白Ⅰ的阳性率高于心肌酶学的阳性率,血清中出现时间早于心肌酶学,cTnI测定对诊断急性心肌梗塞具有敏感性高于心肌酶学测定的特征。结论肌钙蛋白Ⅰ检测方便、快捷,对急性心肌梗塞的早期诊断具有较高的特异性和敏感性,诊断价值优于其他心肌酶的测定。
Objective To investigate the clinical value of cTnI in the early diagnosis of acute myocardial infarction (AMI). Methods Serum levels of troponin I in 29 patients with acute myocardial infarction (AMI) at different time points after admission were measured qualitatively and their activities of creatine kinase (CK), creatine kinase CK (CK), lactate dehydrogenase (LDH) . The test results were compared. Results The incidence of acute myocardial infarction was 3 to 6 hours. The positive rate of serum troponin I was higher than the positive rate of myocardial enzymology, the serum appeared earlier than myocardial enzyme, and cTnI was sensitive to the diagnosis of acute myocardial infarction Characteristics of myocardial enzymometry. Conclusion The detection of troponin Ⅰ is convenient and quick. It has high specificity and sensitivity for the early diagnosis of acute myocardial infarction. The diagnostic value of troponin Ⅰ is superior to that of other myocardial enzymes.